There is so much talk of issues with NDT. And I have already written one post about it. I hope to be a sobering voice. I see a lot of stress and worry created, especially in the US. We take it more easy here in Europe.
Is there any need for worry? No, you don’t need to worry. Only people who do not know anything about their optimal levels, or how to monitor them, need to worry. You will learn how to do these things, if you don’t already know it. I will teach you. Then you just adjust your dose as needed.
Because thyroid meds will continue to fluctuate also in the future. And not only NDT, synthetic meds differ in their hormone levels as well. You can read more about that here.
Synthetic T4 meds like Synthroid and Levo, are legally allowed to vary between 95 and 105 % of the given amount. So your current batch can be 10 % stronger or weaker than your previous batch. NDT and synthetic T3 medicin is allowed to vary between 90 and 110 %. The current recall of Nature Throid and Westhroid is for medicine that might contain 87 % of the given amount. That is 3 % less than what is allowed. OMG!
I started thinking, I wonder if all thyroid issue from pigs is the same. And loe and behold, it is not. Pigs’ thyroid levels vary with age, gender and even breed. So it may be nigh impossible to always guarantee equal hormone content.
This is the world we live in, all thyroid meds vary in hormone content.
Did you know that it’s best to start treatment with estrogen BEFORE 60? The study that scared everybody from taking estrogen 25 years ago had many flaws. I will review them. It’s estrogene in conjunction with synthetic progesterone, gestagen, that can lead to an increased risk for breast cancer and heart issues. And especially if starting after 60. It’s also very important what kind of estrogen you take. Estradiol, which is plantbased, is better for us than conjugated estrogens. Premarin. Premarin is made from the urine from pregnant mares. The mares are being abused in the process; horrible to read about. And transdermal is better than oral.
Nb! When you take ORAL estrogen, the total hormones become higher. The free hormones must be taken.
Natural progesterone is also better than synthetic. It’s also plant based, derived from the same plant as oestradiol, wild yam. It’s only the natural that is called progesterone, synthetic is called things like gestagen and progestins.
If you still have your uterus, it’s very important to take progesterone when you use estrogen. If not, the uterine wall might become thicker. It seems it’s mostly natural progesterone in pillform that has this effect on the uterine wall. Though my progesterone cream kept my uterine wall normal.
One does not find any increased risk of breast cancer when estrogen is combined with natural progesterone, only when combined with synthetic. Natural progesterone also has a beneficial influence on the cardiovascular system.
Testosterone is also very important for us women, not only for men. It’s important for sexual excitement, the ability to orgasm, muscle strength and our bones. And the ability to hold our water! Anyone having issues with that?😜
Basic guide for you who are new to thyroid issues
I wanted to make the guide I wish I had had. Way back when, more than 20 years ago. Knowledge that could have saved me a lot of suffering. Maybe I would have been more healthy today.
So it is my hope, this info could help you. Of course, there is so much info today, compared to earlier. But maybe there is too much info for someone new to this. I hope I can make it. if not easy, then possible to understand.
I don’t know how you are feeling at present. If you have just been diagnosed with hypothyroid, with autoimmune thyreoditis, have had your thyroid removed or maybe you are struggling to get a diagnosis. Maybe your doctor is dismissing you, but you know something is wrong.
This is a translation of an article published in the Norwegian Journal for Physicians, Tidsskriftet, https://tidsskriftet.no/2018/03/kronikk/ostrogener-i-menopausen-p%C3%A5-tide-endre-anbefalingene
New studies show, that treatment with estrogen with start before age 60, are for the most part positive. It’s time to change the recommendations.
Reverse T3 is not the big bad wolf in our thyroid system. It is a necessary brake where FT3 is the gas pedal. We can get too much RT3 when we take more T4 medicine than we are able to convert to T3. Could be just too high dose, or that we don’t convert well. Other conditions can increase RT3 too much as well. It’s a good idea to test RT3 from time to time. But it is not necessary to test all the time.
I will look at myths and misunderstandings around RT3. for one thing, RT3 does not block T3 by occupying T3 receptors. Nor does it hinder T4 to T3 conversion. If there is a big bad wolf, it’s deiodinase 3, D3. It’s D3 who converts T4 to RT3, and who hinders T3 from attaching to the T3 receptors i the cell nucleus.
But there are no “wolves” in our thyroid system. Only participants with their own roles to play. And the better we understand the play, the more can we hopefully optimize our thyroid levels and feel better.
I will look at what causes too high RT3, and what one can do bring it down.
As with LDN, I am no expert on Iodine. I am on it myself, have been for about 6 minths here in may 2020. I will be updating the post as I go along. I will be absolutly honest about what is happening. I won’t be writing too much about the complicated aspects of Iodine. But I want to present some of it. So if you are mostly interested in the more practical aspects and concrete tips, scroll down to “The Protocol”.
THE WOLFF/CHAIKOFF EFFECT
Since I began reading about Iodine, I have realized most of us lack Iodine. In 2007, I was a patient at a national center for thyroid disease in Oslo, Norway. Chief Physician Ingrid Norheim told me, avoid all kinds of Iodine. Don’t take a multivitamin containing Iodine. I listened and believed her. She suffered from the Iodine fear that has plagued the world the past 70 years. Ever since Wolff and Chaikoff’s study from 1948, link to the Wolff / Chaikoff study. The study says that big doses of iodine that exceeds a certain level in the blood, 0,2 mg/L, will hinder inorganic iodine from organification inside the thyroid, that is, there will be less thyroidhormone produced. So one will become hypothyroid. G.E. Abraham, the nestor in the Iodine field, says these rats that were given large doses of Iodine, didn’t become hypothyroid. And their thyroid levels weren’t even measured, not before or after the Iodine was injected, link to G.E. Abrahams article.
NO, NDT hasn’t gone bad. That is the short answer. I take NDT myself, and it works just fine.
I see people claiming, NDT is no good anymore. That it is better to take synthetic T4/T3 now. I think this is very serious, that this incorrect, untrue info is being spread in the Facebook groups. It stems from STTM, Stop the Thyroid Madness, and its Facebook group, Adrenal Fatigue and Thyroid Care. STTM is a site that has contributed so much, and I am sad to see, there is such black and white thinking going on. This issue isn’t black and white.
How do I convert my T4 dose to NDT?
This is a question one sees often in the thyroid Facebook groups. There is a lot of confusion and insecurity around this. Which is not so strange, as there is very little good info on the topic. The conversion tables the NDT (thyroid) producers themselves provide are ridiculously low. They are wrong, wrong, wrong. I don’t understand how they think at all. If they do. Think. One would be seriously under dosed if adhering to those guidelines. And if one’s doctor reads them, one could get serious problems. I don’t know how many doctors read these instructions. I hope they don’t. Here is a table from Nature Troid as a (bad) example.
I have translated some of Thyroid Patients Canada’ articles on conversion into Norwegian. These articles are very interesting, esp this one, https://thyroidpatients.ca/2019/11/12/the-basics-of-thyroid-hormone-action-transport-and-conversion/
Most of the hormone conversion, T4 to T3 happens outside the thyroid. though there are big individual differences how much. There are 3 enzymes responsible for this conversion, D1, D2 and D3. They do a lot more than convert T4 to T3 though.