I have got to admit, I have been very ignorant about how NDT is made. I have believed that NDT and glandular supplements, like Metavive and Thyrogold, were virtually the same. And I have been telling people that. They are not, glandular is a much weaker product. I could be embarrassed about this. But I choose not to. This only proves my point, that there is so much to learn about this thyroid issue. Let’s try to stay openminded, and just admit when we are mistaken. That is the only way to learn something new.
I have this info from Chris at Pim Pom products, also the photos. Most of it is a direct quote from him. I have just added a little. Thanks, Chris!
There is so much talk of issues with NDT. And I have already written one post about it. I hope to be a sobering voice. I see a lot of stress and worry created, especially in the US. We take it more easy here in Europe.
Is there any need for worry? No, you don’t need to worry. Only people who do not know anything about their optimal levels, or how to monitor them, need to worry. You will learn how to do these things, if you don’t already know it. I will teach you. Then you just adjust your dose as needed.
Because thyroid meds will continue to fluctuate also in the future. And not only NDT, synthetic meds differ in their hormone levels as well. You can read more about that here.
Synthetic T4 meds like Synthroid and Levo, are legally allowed to vary between 95 and 105 % of the given amount. So your current batch can be 10 % stronger or weaker than your previous batch. NDT and synthetic T3 medicin is allowed to vary between 90 and 110 %. The current recall of Nature Throid and Westhroid is for medicine that might contain 87 % of the given amount. That is 3 % less than what is allowed. OMG!
I started thinking, I wonder if all thyroid issue from pigs is the same. And loe and behold, it is not. Pigs’ thyroid levels vary with age, gender and even breed. So it may be nigh impossible to always guarantee equal hormone content.
This is the world we live in, all thyroid meds vary in hormone content.
Basic guide for you who are new to thyroid issues
I wanted to make the guide I wish I had had. Way back when, more than 20 years ago. Knowledge that could have saved me a lot of suffering. Maybe I would have been more healthy today.
So it is my hope, this info will help you. Of course, there is so much info today, compared to earlier. But maybe there is too much info for someone new to this. I hope I can make it,if not easy, then at least possible to understand.
I don’t know how you are feeling at present. If you have just been diagnosed with hypothyroid, with autoimmune thyreoditis, have had your thyroid removed or maybe you are struggling to get a diagnosis. Maybe your doctor is dismissing you, but you feel sick and know something is wrong.
Reverse T3 is not the big bad wolf in our thyroid system. It is a necessary brake where FT3 is the gas pedal. We can get too much RT3 when we take more T4 medicine than we are able to convert to T3. Could be just too high dose, or that we don’t convert well. Other conditions can increase RT3 too much as well. It’s a good idea to test RT3 from time to time. But it is not necessary to test all the time.
I will look at myths and misunderstandings around RT3. for one thing, RT3 does not block T3 by occupying T3 receptors. Nor does it hinder T4 to T3 conversion. If there is a big bad wolf, it’s deiodinase 3, D3. It’s D3 who converts T4 to RT3, and who hinders T3 from attaching to the T3 receptors i the cell nucleus.
But there are no “wolves” in our thyroid system. Only participants with their own roles to play. And the better we understand the play, the more can we hopefully optimize our thyroid levels and feel better.
I will look at what causes too high RT3, and what one can do bring it down.
NO, NDT hasn’t gone bad. That is the short answer. I take NDT myself, and it works just fine.
I see people claiming, NDT is no good anymore. That it is better to take synthetic T4/T3 now. I think this is very serious, that this incorrect, untrue info is being spread in the Facebook groups. It stems from STTM, Stop the Thyroid Madness, and its Facebook group, Adrenal Fatigue and Thyroid Care. STTM is a site that has contributed so much, and I am sad to see, there is such black and white thinking going on. This issue isn’t black and white.
How do I convert my T4 dose to NDT?
This is a question one sees often in the thyroid Facebook groups. There is a lot of confusion and insecurity around this. Which is not so strange, as there is very little good info on the topic. The conversion tables the NDT (thyroid) producers themselves provide are ridiculously low. They are wrong, wrong, wrong. I don’t understand how they think at all. If they do. Think. One would be seriously under dosed if adhering to those guidelines. And if one’s doctor reads them, one could get serious problems. I don’t know how many doctors read these instructions. I hope they don’t. Here is a table from Nature Troid as a (bad) example.
This is not really a post. I have translated Tania Sona Smith’s article, https://thyroidpatients.ca/2019/11/25/free-t3-peaks-and-valleys-in-t3-and-ndt-therapy/ , into Norwegian. For every Norwegian page, I want there to be a corresponding English, and vice versa.
This is just a presentation of Tania’s piece. She is looking into the reseach on how Ft3 behaves after dosing with T3 containing medicine. Actually, there is not really any good studies on the subject . There is a study on FT3 after a single dose of T3. But that is not what most people take when dosing with T3. We do multidoses. There is no study on FT3 when multidosing, but there is one on T3, that is total T3. Where I live in Denmark, we cannot have FT3 tested. The endoes have forbidden it, they claim, FT3 fluctuates too much, it cannot be trusted. How do they know? With no studies? Anyway, FT3 and T3 follow each other in most instances . With a very important exception, when we take estrogen orally. Then both T4 and T3 becomes higher and FT4 and FT3 lower. So VERY important to have the frees tested.
This is just a short abstract of Thyroid Patients Canada’s article on Triac, https://thyroidpatients.ca/2020/01/02/when-dosing-t3-you-get-higher-levels-of-triac/ . I just want to draw your attention to this metabolite. The quistionmark on the image, is meant to signify my surprice when learning of Triac. I had never heard of this thyroidhormone metabolite until I read Tania’s post. It is quite strange, as it has been studied since the 1950ies. I don’t think many of our doctors have ever heard of it.
So what is it? It is a thyroidhormone metabolite like FT4 and FT3 are. It acts much as FT3, it’s abbreveration is TA3. It has a much shorter halflife than FT3, about 6 times faster.